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Biochemistry (Moscow), Volume 90(6), 2025

Genetic Technologies in Medicine, Agriculture, and Biotechnology (Special Issue). Guest Editors: Dmitry S. Kostyushev and Andrey A. Zamyatnin, Jr.

Preface to the Special Issue “Genetic Technologies in Medicine, Agriculture, and Biotechnology” Dmitry S. Kostyushev and Andrey A. Zamyatnin, Jr.
649 [Abstract] [Full Article] [Reprint (PDF)]

REVIEW: The Role of m6A-RNA Methylation in the Development, Progression, and Treatment Response of Bladder Cancer Tatiana Sinyagovskaya, Yuliya Li, Natalya Vinchevskaya-Khmelnitskaya, Aisha Agabalaeva, Natalia Ponomareva, Sergey Brezgin, Irina Goptar, Vladimir Chulanov, Alim Dymov, Andrey Vinarov, Dmitry Kostyushev, and Anastasiya Kostyusheva
650 [Abstract] [Full Article] [Reprint (PDF)]

Diagnostic and Prognostic Potential of Circulating miR-1301-3p, miR-106a-5p, miR-129-5p, miR-3613-3p, and miR-647 microRNAs in Gastric Cancer Irina V. Bure, Ekaterina A. Vetchinkina, Alexei I. Kalinkin, Ekaterina B. Kuznetsova, Alevtina E. Kiseleva, Ekaterina A. Alekseeva, Nikolay S. Esetov, and Marina V. Nemtsova
671 [Abstract] [Full Article] [Reprint (PDF)]

REVIEW: Transcriptional Biomarkers in the Diagnosis of Genetic Disorders: Opportunities, Challenges, and Prospects for Application Lidia N. Nefedova and Tatiana N. Krasnova
683 [Abstract] [Full Article] [Reprint (PDF)]

REVIEW: Telomere Length and Telomerase Activity as Biomarkers in the Diagnostics and Prognostics of Pathological Conditions Elizaveta Yu. Moskaleva, Alexander I. Glukhov, Alexander S. Zhirnik, Olga V. Vysotskaya, and Svetlana A. Vorobiova
700 [Abstract] [Full Article] [Reprint (PDF)]

REVIEW: Selection of UTRs in mRNA-Based Gene Therapy and Vaccines Ilya A. Volkhin, Anastasia Iu. Paremskaia, Maria A. Dashian, Darya S. Smeshnova, Roman E. Pavlov, Olga N. Mityaeva, Pavel Yu. Volchkov, and Andrei A. Deviatkin
725 [Abstract] [Full Article] [Reprint (PDF)]

Multiepitope mRNA Vaccine mRNA-mEp21-FL-IDT Provides Efficient Protection against M. tuberculosis Alisa A. Kazakova, Galina S. Shepelkova, Ivan S. Kukushkin, Vladimir V. Yeremeev, Roman A. Ivanov, and Vasiliy V. Reshetnikov
754 [Abstract] [Full Article] [Reprint (PDF)]

Selection of Optimal pegRNAs to Enhance Efficiency of Prime Editing in AT-Rich Genome Regions Olga V. Volodina, Anna G. Demchenko, Arina A. Anuchina, Oxana P. Ryzhkova, Valeriia A. Kovalskaya, Ekaterina V. Kondrateva, Vyacheslav Y. Tabakov, Alexander V. Lavrov, and Svetlana A. Smirnikhina
773 [Abstract] [Full Article] [Reprint (PDF)]

REVIEW: Progress in CRISPR/CAS13-Mediated Suppression of Influenza A and SARS-CoV-2 Virus Infection in in vitro and in vivo Models Alisa A. Kazakova, Elena I. Leonova, Julia V. Sopova, Angelina V. Chirinskaite, Ekaterina S. Minskaya, Ivan S. Kukushkin, Roman A. Ivanov, and Vasiliy V. Reshetnikov
786 [Abstract] [Full Article] [Reprint (PDF)]

REVIEW: Biotechnological Approaches to Plant Antiviral Resistance: CRISPR-Cas or RNA Interference? Natalia O. Kalinina, Nadezhda A. Spechenkova and Michael E. Taliansky
804 [Abstract] [Full Article] [Reprint (PDF)]

Designing a Thermostable Mini-Intein for Intein-Mediated Purification of Recombinant Proteins and Peptides Andrey A. Karanov, Evgeniy A. Zayats, Maria A. Kostromina, Yulia A. Abramchik, Aleksandra R. Sharafutdinova, Maria S. Surkova, Andrey A. Zamyatnin, Jr., and Roman S. Esipov
818 [Abstract] [Full Article] [Reprint (PDF)]