Interaction of Transketolase from Human Tissues with Substrates

---

L. E. Meshalkina^*, O. N. Solovjeva, and G. A. Kochetov

Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia; fax: (495) 939-3181; E-mail: luda@genebee.msu.ru

^* To whom correspondence should be addressed.

Received January 12, 2011; Revision received April 1, 2011

---

The Michaelis constant values for substrates of transketolase from human tissues were determined over a wide range of substrate concentrations. It is shown that K_m values determined by other authors are significantly overestimated and explained why this is so.

---

KEY WORDS: human tissues transketolase, thiamine diphosphate, K_m for substrates of human tissues transketolase

DOI: 10.1134/S0006297911090112

---