Biochemistry and Molecular Biology of Vitamin B6 and PQQ-dependent
Proteins (Iriarte, A. J., Kagan, H. M., and Martinez-Carrion, M., eds.,
Birkhauser Verlag AG, Basel-Berlin-Boston, 2000, 400 p.)
The most recent information on proteins dependent upon Vitamin B6,
pyrroloquinoline quinone (PQQ), or other quinones for function are
included in this volume. It is a compilation of recent advances in the
understanding of these proteins' structures, mechanisms of action, and
their biological roles and functions. In addition, the book contains
sections devoted to the mechanisms of folding and to addressing the
molecular physiology and pathology of these families of proteins, which
are of intense biomedical interest. Emerging information regarding the
participation of these proteins in enzymatic activity and their
significance in biotechnology application, such as the use of specific
inhibitors, is also included. The topics treated comprise genetic
regulation, evolutionary and cell biological aspects, as well as the
latest information on structures and mechanisms operating in these
proteins.
A. V. Medvedev
