Colloidal Gold in Solid-Phase Assays. A Review

L. A. Dykman^1,2 and V. A. Bogatyrev¹

¹Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, pr. Entuziastov 13, Saratov, 410015 Russia; E-mail: root@physchemlab.saratov.su

²To whom correspondence should be addressed.

Submitted August 28, 1996; revision submitted January 6, 1997.

This review summarizes the data on the application of colloidal gold preparations in solid-phase assays. The possibilities to analyze soluble and particle antigens adsorbed on solid carriers, and the limitations imposed by the application of colloidal gold preparations are considered. Certain aspects of the technology of preparation and application of colloidal gold preparations are discussed.

KEY WORDS: colloidal gold, solid-phase assay, silver enhancement, sol particle analysis.

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